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ro.owl
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ro.owl
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<?xml version="1.0"?>
<!DOCTYPE rdf:RDF [
<!ENTITY owl "http://www.w3.org/2002/07/owl#" >
<!ENTITY obo "http://purl.obolibrary.org/obo/" >
<!ENTITY xsd "http://www.w3.org/2001/XMLSchema#" >
<!ENTITY rdfs "http://www.w3.org/2000/01/rdf-schema#" >
<!ENTITY rdf "http://www.w3.org/1999/02/22-rdf-syntax-ns#" >
<!ENTITY oboInOwl "http://www.geneontology.org/formats/oboInOwl#" >
]>
<rdf:RDF xmlns="&obo;ro.owl#"
xml:base="&obo;ro.owl"
xmlns:obo="http://purl.obolibrary.org/obo/"
xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
xmlns:owl="http://www.w3.org/2002/07/owl#"
xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#">
<owl:Ontology rdf:about="&obo;ro.owl">
<owl:imports rdf:resource="https://raw.github.com/ontodev/bfo/master/bfo-1.2.owl"/>
<owl:imports rdf:resource="https://raw.github.com/ontodev/bfo/master/ontology-metadata.owl"/>
<owl:versionIRI rdf:resource="&obo;ro/2012-07-11/ro.owl"/>
</owl:Ontology>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Annotation properties
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<owl:AnnotationProperty rdf:about="&obo;RO_0002161">
<rdfs:label rdf:datatype="&xsd;string">never in taxon</rdfs:label>
<obo:IAO_0000119>PMID:17921072</obo:IAO_0000119>
<obo:IAO_0000112>tooth SubClassOf 'never in taxon' value 'Aves'</obo:IAO_0000112>
<obo:IAO_0000425>?X DisjointWith RO_0002162 some ?Y </obo:IAO_0000425>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PMID:20973947</obo:IAO_0000119>
<obo:IAO_0000115>x never in taxon T if and only if T is a class, and x does not instantiate the class expression "in taxon some T". Note that this is a shortcut relation, and should be used as a hasValue restriction in OWL.</obo:IAO_0000115>
</owl:AnnotationProperty>
<owl:AnnotationProperty rdf:about="&obo;IAO_id"/>
<owl:AnnotationProperty rdf:about="&oboInOwl;shorthand">
<rdfs:label rdf:datatype="&xsd;string">shorthand</rdfs:label>
</owl:AnnotationProperty>
<owl:AnnotationProperty rdf:about="&rdfs;label"/>
<owl:AnnotationProperty rdf:about="&obo;IAO_0000424"/>
<owl:AnnotationProperty rdf:about="&obo;IAO_0000115">
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000122"/>
</owl:AnnotationProperty>
<rdf:Description rdf:about="&obo;IAO_0000116">
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000122"/>
</rdf:Description>
<owl:AnnotationProperty rdf:about="&obo;IAO_0000412">
<rdfs:label xml:lang="en">imported from</rdfs:label>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
</owl:AnnotationProperty>
<owl:AnnotationProperty rdf:about="&obo;IAO_0000119">
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000122"/>
</owl:AnnotationProperty>
<rdf:Description rdf:about="&obo;IAO_0000232">
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000122"/>
</rdf:Description>
<owl:AnnotationProperty rdf:about="&obo;IAO_0000426"/>
<owl:AnnotationProperty rdf:about="&obo;IAO_0000117">
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000122"/>
</owl:AnnotationProperty>
<owl:AnnotationProperty rdf:about="&obo;IAO_0000425"/>
<rdf:Description rdf:about="&obo;IAO_0000118">
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
</rdf:Description>
<owl:AnnotationProperty rdf:about="&obo;IAO_0000111">
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000122"/>
</owl:AnnotationProperty>
<owl:AnnotationProperty rdf:about="&obo;IAO_0000112">
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000122"/>
</owl:AnnotationProperty>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Datatypes
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Object Properties
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!-- http://purl.obolibrary.org/obo/RO_0000300 -->
<owl:ObjectProperty rdf:about="&obo;RO_0000300">
<rdf:type rdf:resource="&owl;TransitiveProperty"/>
<rdfs:label xml:lang="en">in neural circuit with</rdfs:label>
<obo:IAO_0000426 rdf:datatype="&xsd;string">(forall (?x ?y)
(iff
(neural_circuit_path ?x ?y)
(and
("neuron ; CL_0000540" ?x)
("neuron ; CL_0000540" ?y)
(or
(synapsed_by ?x ?y)
(synapsed_to ?x ?y)))))
(forall (...s ?x ?y ?z)
(iff
(neural_circuit_path ...s ?x ?y ?z)
(and
(neural_circuit_path ...s ?x ?y)
("neuron ; CL_0000540" ?z)
(or
(synapsed_by ?y ?z)
(synapsed_to ?y ?z)))))
(forall (?x ?y)
(iff
(in_neural_circuit_with ?x ?y)
(exists (...s)
(neural_circuit_path ?x ...s ?y)))) </obo:IAO_0000426>
<obo:IAO_0000115 xml:lang="en">A relation that holds between two neurons connected directly via a synapse, or indirectly via a series of synaptically connected neurons.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0000301 -->
<owl:ObjectProperty rdf:about="&obo;RO_0000301">
<rdf:type rdf:resource="&owl;TransitiveProperty"/>
<rdfs:label xml:lang="en">upstream in neural circuit with</rdfs:label>
<obo:IAO_0000426 rdf:datatype="&xsd;string">(forall (?x ?y)
(iff
(upstream_neural_circuit_path ?x ?y)
(and
("neuron ; CL_0000540" ?x)
("neuron ; CL_0000540" ?y)
(synapsed_to ?x ?y))))
(forall (...s ?x ?y ?z)
(iff
(upstream_neural_circuit_path ...s ?x ?y ?z )
(and
(upstream_neural_circuit_path ...s ?x ?y)
("neuron ; CL_0000540" ?z)
(synapsed_to ?y ?z))))
(forall (?x ?y)
(iff
(upstream_in_neural_circuit_with ?x ?y)
(exists (...s)
(upstream_neural_circuit_path ?x ...s ?y))))</obo:IAO_0000426>
<obo:IAO_0000115 xml:lang="en">A relation that holds between a neuron that is synapsed_to another neuron or a neuron that is connected indirectly to another by a chain of neurons, each synapsed_to the next.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
<rdfs:subPropertyOf rdf:resource="&obo;RO_0000300"/>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0000302 -->
<owl:ObjectProperty rdf:about="&obo;RO_0000302">
<rdf:type rdf:resource="&owl;TransitiveProperty"/>
<rdfs:label xml:lang="en">downstream in neural circuit with</rdfs:label>
<obo:IAO_0000426 rdf:datatype="&xsd;string">(forall (?x ?y)
(iff
(downstream_neural_circuit_path ?x ?y)
(and
("neuron ; CL_0000540" ?x)
("neuron ; CL_0000540" ?y)
(synapsed_by ?x ?y))))
(forall (...s ?x ?y ?z)
(iff
(downstream_neural_circuit_path ...s ?x ?y ?z )
(and
(downstream_neural_circuit_path ...s ?x ?y)
("neuron ; CL_0000540" ?z)
(synapsed_by ?y ?z))))
(forall (?x ?y)
(iff
(downstream_in_neural_circuit_with ?x ?y)
(exists (...s)
(downstream_neural_circuit_path ?x ...s ?y))))
</obo:IAO_0000426>
<obo:IAO_0000115 xml:lang="en">A relation that holds between a neuron that is synapsed_to another neuron or a neuron that is connected indirectly to another by a chain of neurons, each synapsed_to the next.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
<rdfs:subPropertyOf rdf:resource="&obo;RO_0000300"/>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0001000 -->
<owl:ObjectProperty rdf:about="&obo;RO_0001000">
<rdfs:label xml:lang="en">derives from</rdfs:label>
<rdfs:comment>Original def from OBO_REL: instance level derives_from holds between distinct material continuants when one succeeds the other across a temporal divide in such a way that at least a biologically significant portion of the matter of the earlier continuant is inherited by the later</rdfs:comment>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
<rdfs:subPropertyOf rdf:resource="&owl;topObjectProperty"/>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002001 -->
<owl:ObjectProperty rdf:about="&obo;RO_0002001">
<rdf:type rdf:resource="&owl;TransitiveProperty"/>
<rdfs:label xml:lang="en">aligned with</rdfs:label>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002100 -->
<owl:ObjectProperty rdf:about="&obo;RO_0002100">
<rdfs:label xml:lang="en">has soma location</rdfs:label>
<obo:IAO_0000424><http://purl.obolibrary.org/obo/BFO_0000051> some (
<http://purl.obolibrary.org/obo/GO_0043025> and <http://purl.obolibrary.org/obo/BFO_0000050> some ?Y)</obo:IAO_0000424>
<obo:IAO_0000115 xml:lang="en">Relation between a neuron and an anatomical structure that its soma is part of.</obo:IAO_0000115>
<obo:IAO_0000111 xml:lang="en">soma part of</obo:IAO_0000111>
<rdfs:domain rdf:resource="&obo;CL_0000540"/>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
<rdfs:subPropertyOf rdf:resource="&obo;RO_0002131"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="&obo;RO_0002100"/>
<rdf:Description rdf:about="&obo;BFO_0000050"/>
</owl:propertyChainAxiom>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002101 -->
<owl:ObjectProperty rdf:about="&obo;RO_0002101">
<rdfs:label xml:lang="en">fasciculates with</rdfs:label>
<obo:IAO_0000426 rdf:datatype="&xsd;string">(forall (?x ?y)
(iff
(fasciculates_with ?x ?y)
(exists (?nps ?npbs)
(and
("neuron ; CL_0000540" ?x)
("neuron projection bundle ; CARO_0001001" ?y)
("neuron projection segment ; CARO_0001502" ?nps)
("neuron projection bundle segment ; CARO_0001500' " ?npbs)
(part_of ?npbs ?y)
(part_of ?nps ?x)
(part_of ?nps ?npbs)
(forall (?npbss)
(if
(and
("neuron projection bundle subsegment ; CARO_0001501" ?npbss)
(part_of ?npbss ?npbs)
)
(overlaps ?nps ?npbss)
))))))</obo:IAO_0000426>
<obo:IAO_0000118>fasciculates with</obo:IAO_0000118>
<obo:IAO_0000115 xml:lang="en">relationship between a neuron and a neuron projection bundle (e.g.- tract or nerve bundle) that one or more of its projections travels through.
</obo:IAO_0000115>
<rdfs:range rdf:resource="&obo;CARO_0001001"/>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
<rdfs:subPropertyOf rdf:resource="&obo;RO_0002131"/>
<rdfs:domain>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="&obo;CL_0000540"/>
<owl:Restriction>
<owl:onProperty rdf:resource="&obo;BFO_0000050"/>
<owl:someValuesFrom rdf:resource="&obo;CL_0000540"/>
</owl:Restriction>
</owl:unionOf>
</owl:Class>
</rdfs:domain>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002102 -->
<owl:ObjectProperty rdf:about="&obo;RO_0002102">
<rdfs:label xml:lang="en">axon synapses in</rdfs:label>
<obo:IAO_0000424><http://purl.obolibrary.org/obo/BFO_0000051> some (
<http://purl.obolibrary.org/obo/GO_0030424> and <http://purl.obolibrary.org/obo/BFO_0000051> some (
<http://purl.obolibrary.org/obo/GO_0042734> and <http://purl.obolibrary.org/obo/BFO_0000050> some (
<http://purl.obolibrary.org/obo/GO_0045202> and <http://purl.obolibrary.org/obo/BFO_0000050> some ?Y)))</obo:IAO_0000424>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000115 xml:lang="en">Relation between a neuron and some structure its axon forms (chemical) synapses in.</obo:IAO_0000115>
<rdfs:domain rdf:resource="&obo;CL_0000540"/>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
<rdfs:subPropertyOf rdf:resource="&obo;RO_0002113"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="&obo;RO_0002102"/>
<rdf:Description rdf:about="&obo;BFO_0000050"/>
</owl:propertyChainAxiom>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002103 -->
<owl:ObjectProperty rdf:about="&obo;RO_0002103">
<rdfs:label xml:lang="en">synapsed by</rdfs:label>
<obo:IAO_0000424><http://purl.obolibrary.org/obo/BFO_0000051> some (<http://purl.obolibrary.org/obo/GO_0045211> that part_of some (<http://purl.obolibrary.org/obo/GO_0045202> that has_part some (<http://purl.obolibrary.org/obo/GO_0042734> that <http://purl.obolibrary.org/obo/BFO_0000050> some Y?)))</obo:IAO_0000424>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000115 xml:lang="en">Relation between an anatomical structure (including cells) and a neuron that chemically synapses to it. </obo:IAO_0000115>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
<rdfs:subPropertyOf rdf:resource="&obo;RO_0000301"/>
<rdfs:range>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="&obo;CL_0000540"/>
<owl:Restriction>
<owl:onProperty rdf:resource="&obo;BFO_0000050"/>
<owl:someValuesFrom rdf:resource="&obo;CL_0000540"/>
</owl:Restriction>
</owl:unionOf>
</owl:Class>
</rdfs:range>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002104 -->
<owl:ObjectProperty rdf:about="&obo;RO_0002104">
<rdfs:label xml:lang="en">has plasma membrane part</rdfs:label>
<obo:IAO_0000424><http://purl.obolibrary.org/obo/BFO_0000051> some (<http://purl.obolibrary.org/obo/GO_0005886> and <http://purl.obolibrary.org/obo/BFO_0000051> some ?Y)</obo:IAO_0000424>
<obo:IAO_0000117>Lindsay Cowell</obo:IAO_0000117>
<obo:IAO_0000117>Alexander Diehl</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000112 xml:lang="en">Every B cell[CL_0000236] has plasma membrane part some immunoglobulin complex[GO_0019814]</obo:IAO_0000112>
<obo:IAO_0000115>Holds between a cell c and a protein complex or protein p if and only if that cell has as part a plasma_membrane[GO:0005886], and that plasma membrane has p as part.</obo:IAO_0000115>
<obo:IAO_0000119 xml:lang="en">PMID:19243617</obo:IAO_0000119>
<rdfs:subPropertyOf rdf:resource="&obo;BFO_0000051"/>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002110 -->
<owl:ObjectProperty rdf:about="&obo;RO_0002110">
<rdfs:label xml:lang="en">has postsynaptic terminal in</rdfs:label>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000115 xml:lang="en">Relation between a neuron and some structure (e.g.- a brain region) in which it receives (chemical) synaptic input. </obo:IAO_0000115>
<obo:IAO_0000424>http://purl.obolibrary.org/obo/BFO_0000051 some (
http://purl.org/obo/owl/GO#GO_0045211 and http://purl.obolibrary.org/obo/BFO_0000050 some (
http://purl.org/obo/owl/GO#GO_0045202 and http://purl.obolibrary.org/obo/BFO_0000050 some ?Y))</obo:IAO_0000424>
<obo:IAO_0000118 xml:lang="en">synapsed in</obo:IAO_0000118>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
<owl:inverseOf rdf:resource="&obo;RO_0002102"/>
<rdfs:subPropertyOf rdf:resource="&obo;RO_0002130"/>
<rdfs:domain>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="&obo;CL_0000540"/>
<owl:Restriction>
<owl:onProperty rdf:resource="&obo;BFO_0000050"/>
<owl:someValuesFrom rdf:resource="&obo;CL_0000540"/>
</owl:Restriction>
</owl:unionOf>
</owl:Class>
</rdfs:domain>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="&obo;RO_0002110"/>
<rdf:Description rdf:about="&obo;BFO_0000050"/>
</owl:propertyChainAxiom>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002111 -->
<owl:ObjectProperty rdf:about="&obo;RO_0002111">
<rdfs:label xml:lang="en">releases neurotransmitter</rdfs:label>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
<rdfs:subPropertyOf rdf:resource="&owl;topObjectProperty"/>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002113 -->
<owl:ObjectProperty rdf:about="&obo;RO_0002113">
<rdfs:label xml:lang="en">has presynaptic terminal in</rdfs:label>
<obo:IAO_0000424 xml:lang="en"><http://purl.obolibrary.org/obo/BFO_0000051> some (<http://purl.obolibrary.org/obo/GO_0042734> that <http://purl.obolibrary.org/obo/BFO_0000050> some (<http://purl.obolibrary.org/obo/GO_0045202> that <http://purl.obolibrary.org/obo/BFO_0000050> some Y?)</obo:IAO_0000424>
<obo:IAO_0000115 xml:lang="en">Relation between a neuron and some structure (e.g.- a brain region) in which it receives (chemical) synaptic input.</obo:IAO_0000115>
<obo:IAO_0000118 xml:lang="en">synapses in</obo:IAO_0000118>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
<rdfs:subPropertyOf rdf:resource="&obo;RO_0002130"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="&obo;RO_0002113"/>
<rdf:Description rdf:about="&obo;BFO_0000050"/>
</owl:propertyChainAxiom>
<rdfs:domain>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="&obo;CL_0000540"/>
<owl:Restriction>
<owl:onProperty rdf:resource="&obo;BFO_0000050"/>
<owl:someValuesFrom rdf:resource="&obo;CL_0000540"/>
</owl:Restriction>
</owl:unionOf>
</owl:Class>
</rdfs:domain>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002120 -->
<owl:ObjectProperty rdf:about="&obo;RO_0002120">
<rdfs:label xml:lang="en">synapsed to</rdfs:label>
<rdfs:comment>N1 synapsed_to some N2
Expands to:
N1 SubclassOf (
has_part some (
‘pre-synaptic membrane ; GO:0042734’ that part_of some (
‘synapse ; GO:0045202’ that has_part some (
‘post-synaptic membrane ; GO:0045211’ that part_of some N2))))</rdfs:comment>
<obo:IAO_0000115 xml:lang="en"> Relation between a neuron and an anatomical structure (including cells) that it chemically synapses to.
</obo:IAO_0000115>
<obo:IAO_0000424><http://purl.obolibrary.org/obo/BFO_0000051> some (<http://purl.obolibrary.org/obo/GO_0042734> that part_of some (<http://purl.obolibrary.org/obo/GO_0045202> that <http://purl.obolibrary.org/obo/BFO_0000051> some (<http://purl.obolibrary.org/obo/GO_0045211> that <http://purl.obolibrary.org/obo/BFO_0000050> some Y?)))</obo:IAO_0000424>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
<rdfs:subPropertyOf rdf:resource="&obo;RO_0000302"/>
<rdfs:domain>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="&obo;CL_0000540"/>
<owl:Restriction>
<owl:onProperty rdf:resource="&obo;BFO_0000050"/>
<owl:someValuesFrom rdf:resource="&obo;CL_0000540"/>
</owl:Restriction>
</owl:unionOf>
</owl:Class>
</rdfs:domain>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002121 -->
<owl:ObjectProperty rdf:about="&obo;RO_0002121">
<rdfs:label xml:lang="en">dendrite synapsed in</rdfs:label>
<obo:IAO_0000424><http://purl.obolibrary.org/obo/BFO_0000051> some (
<http://purl.obolibrary.org/obo/GO_0030425> and <http://purl.obolibrary.org/obo/BFO_0000051> some (
http://purl.obolibrary.org/obo/GO_0042734 and <http://purl.obolibrary.org/obo/BFO_0000050> some (
<http://purl.obolibrary.org/obo/GO_0045202> and <http://purl.obolibrary.org/obo/BFO_0000050> some ?Y)))</obo:IAO_0000424>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000115 xml:lang="en">Relation between a neuron and some structure (e.g.- a brain region) in which its dendrite receives synaptic input.
</obo:IAO_0000115>
<rdfs:domain rdf:resource="&obo;CL_0000540"/>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
<rdfs:subPropertyOf rdf:resource="&obo;RO_0002110"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="&obo;RO_0002121"/>
<rdf:Description rdf:about="&obo;BFO_0000050"/>
</owl:propertyChainAxiom>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002130 -->
<owl:ObjectProperty rdf:about="&obo;RO_0002130">
<rdfs:label xml:lang="en">has synaptic terminal in</rdfs:label>
<obo:IAO_0000115>A general relation between a neuron and some structure in which it either chemically synapses to some target or in which it receives (chemical) synaptic input.</obo:IAO_0000115>
<obo:IAO_0000118>has synapse in</obo:IAO_0000118>
<obo:IAO_0000424><http://purl.obolibrary.org/obo/RO_0002131> some (<http://purl.obolibrary.org/obo/GO_0045202> that <http://purl.obolibrary.org/obo/BFO_0000050> some Y?)</obo:IAO_0000424>
<obo:IAO_0000117 xml:lang="en">David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
<rdfs:subPropertyOf rdf:resource="&obo;RO_0002131"/>
<rdfs:domain>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="&obo;CL_0000540"/>
<owl:Restriction>
<owl:onProperty rdf:resource="&obo;BFO_0000050"/>
<owl:someValuesFrom rdf:resource="&obo;CL_0000540"/>
</owl:Restriction>
</owl:unionOf>
</owl:Class>
</rdfs:domain>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="&obo;RO_0002130"/>
<rdf:Description rdf:about="&obo;BFO_0000050"/>
</owl:propertyChainAxiom>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002131 -->
<owl:ObjectProperty rdf:about="&obo;RO_0002131">
<rdfs:label xml:lang="en">overlaps</rdfs:label>
<obo:IAO_0000424>http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.obolibrary.org/obo/BFO_0000050 some ?Y)</obo:IAO_0000424>
<obo:IAO_0000115>x overlaps y if and only if there exists some z such that x has part z and z part of y</obo:IAO_0000115>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
<rdfs:subPropertyOf rdf:resource="&owl;topObjectProperty"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="&obo;RO_0002131"/>
<rdf:Description rdf:about="&obo;BFO_0000050"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="&obo;BFO_0000051"/>
<rdf:Description rdf:about="&obo;RO_0002131"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="&obo;BFO_0000051"/>
<rdf:Description rdf:about="&obo;BFO_0000050"/>
</owl:propertyChainAxiom>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002132 -->
<owl:ObjectProperty rdf:about="&obo;RO_0002132">
<rdfs:label xml:lang="en">has fasciculating neuron projection</rdfs:label>
<obo:IAO_0000426 rdf:datatype="&xsd;string">(forall (?x ?y)
(iff
(has_fasciculating_neuron_projection ?x ?y)
(exists (?nps ?npbs)
(and
("neuron projection bundle ; CARO_0001001" ?x)
("neuron projection ; GO0043005" ?y)
("neuron projection segment ; CARO_0001502" ?nps)
("neuron projection bundle segment ; CARO_0001500" ?npbs)
(part_of ?nps ?y)
(part_of ?npbs ?x)
(part_of ?nps ?npbs)
(forall (?npbss)
(if
(and
("neuron projection bundle subsegment ; CARO_0001501" ?npbss)
(part_of ?npbss ?npbs)
)
(overlaps ?nps ?npbss)
))))))
</obo:IAO_0000426>
<obo:IAO_0000117 xml:lang="en">David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000115 xml:lang="en">The relation between a neuron projection bundle and a neuron projection that is fasciculated with it.</obo:IAO_0000115>
<obo:IAO_0000118 xml:lang="en">has fasciculating component</obo:IAO_0000118>
<rdfs:domain rdf:resource="&obo;CARO_0001001"/>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
<owl:inverseOf rdf:resource="&obo;RO_0002101"/>
<rdfs:subPropertyOf rdf:resource="&obo;RO_0002131"/>
<rdfs:range>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="&obo;CL_0000540"/>
<owl:Restriction>
<owl:onProperty rdf:resource="&obo;BFO_0000050"/>
<owl:someValuesFrom rdf:resource="&obo;CL_0000540"/>
</owl:Restriction>
</owl:unionOf>
</owl:Class>
</rdfs:range>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002134 -->
<owl:ObjectProperty rdf:about="&obo;RO_0002134">
<rdfs:label xml:lang="en">innervates</rdfs:label>
<obo:IAO_0000424><http://purl.obolibrary.org/obo/RO_0002132> some (<http://purl.obolibrary.org/obo/GO_0043005> that (<http://purl.obolibrary.org/obo/RO_0002131> some (<http://purl.obolibrary.org/obo/GO_0045202> that <http://purl.obolibrary.org/obo/BFO_0000050> some Y?)))</obo:IAO_0000424>
<obo:IAO_0000117 xml:lang="en">David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000115 xml:lang="en">Relation between a 'neuron projection bundle' and a region in which one or more of its component neuron projections either synapses to targets or receives synaptic input.
T innervates some R
Expands_to: T has_fasciculating_neuron_projection that synapse_in some R.</obo:IAO_0000115>
<rdfs:domain rdf:resource="&obo;CARO_0001001"/>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
<rdfs:subPropertyOf rdf:resource="&owl;topObjectProperty"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="&obo;RO_0002134"/>
<rdf:Description rdf:about="&obo;BFO_0000050"/>
</owl:propertyChainAxiom>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002150 -->
<owl:ObjectProperty rdf:about="&obo;RO_0002150">
<rdfs:label xml:lang="en">connected to</rdfs:label>
<obo:IAO_0000117 rdf:datatype="&xsd;string">David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000115 rdf:datatype="&xsd;string">X connected_to Y if and only if X and Y share a fiat boundary.</obo:IAO_0000115>
<rdfs:range rdf:resource="&obo;BFO_0000004"/>
<rdfs:domain rdf:resource="&obo;BFO_0000004"/>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002151 -->
<owl:ObjectProperty rdf:about="&obo;RO_0002151">
<rdfs:label xml:lang="en">proper overlaps</rdfs:label>
<obo:IAO_0000426 rdf:datatype="&xsd;string">(forall (?x ?y)
(iff
(proper_overlaps ?x ?y)
(and
(overlaps ?x ?y)
(not (part_of ?x ?y))
(not (part_of ?y ?x)))))</obo:IAO_0000426>
<obo:IAO_0000118 rdf:datatype="&xsd;string">partially overlaps</obo:IAO_0000118>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
<rdfs:subPropertyOf rdf:resource="&obo;RO_0002131"/>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002156 -->
<owl:ObjectProperty rdf:about="&obo;RO_0002156">
<rdf:type rdf:resource="&owl;TransitiveProperty"/>
<rdfs:label rdf:datatype="&xsd;string">derived by descent from</rdfs:label>
<obo:IAO_0000118 rdf:datatype="&xsd;string">ancestral_stucture_of</obo:IAO_0000118>
<obo:IAO_0000115 rdf:datatype="&xsd;string">d derived_by_descent_from a if d is specified by some genetic program that is sequence-inherited-from a genetic program that specifies a.</obo:IAO_0000115>
<obo:IAO_0000118 rdf:datatype="&xsd;string">evolutionarily_descended_from</obo:IAO_0000118>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
<owl:inverseOf rdf:resource="&obo;RO_0002157"/>
<rdfs:subPropertyOf rdf:resource="&owl;topObjectProperty"/>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002157 -->
<owl:ObjectProperty rdf:about="&obo;RO_0002157">
<rdf:type rdf:resource="&owl;TransitiveProperty"/>
<rdfs:label rdf:datatype="&xsd;string">has derived by descendant</rdfs:label>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002158 -->
<owl:ObjectProperty rdf:about="&obo;RO_0002158">
<rdf:type rdf:resource="&owl;SymmetricProperty"/>
<rdf:type rdf:resource="&owl;TransitiveProperty"/>
<rdfs:label rdf:datatype="&xsd;string">shares ancestor with</rdfs:label>
<rdfs:comment rdf:datatype="&xsd;string">VBO calls this homologous_to</rdfs:comment>
<obo:IAO_0000115 rdf:datatype="&xsd;string">two individual entities d1 and d2 stand in a shares_ancestor_with relation if and only if there exists some a such that d1 derived_by_descent_from a and d2 derived_by_descent_from a.</obo:IAO_0000115>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="&obo;RO_0002156"/>
<rdf:Description rdf:about="&obo;RO_0002157"/>
</owl:propertyChainAxiom>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002160 -->
<owl:ObjectProperty rdf:about="&obo;RO_0002160">
<rdfs:label rdf:datatype="&xsd;string">only in taxon</rdfs:label>
<obo:IAO_0000119>PMID:17921072</obo:IAO_0000119>
<obo:IAO_0000115>x only in taxon y if and only if x is in taxon y, and there is no other organism z such that y!=z a and x is in taxon z.</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000116>The original intent was to treat this as a macro that expands to 'in taxon' only ?Y - however, this is not necessary if we instead have supplemental axioms that state that each pair of sibling tax have a disjointness axiom using the 'in taxon' property - e.g.
'in taxon' some Eukaryota DisjointWith 'in taxon' some Eubacteria</obo:IAO_0000116>
<obo:IAO_0000119 xml:lang="en">PMID:20973947</obo:IAO_0000119>
<obo:IAO_0000112>lactation SubClassOf 'only in taxon' some 'Mammalia'</obo:IAO_0000112>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
<rdfs:subPropertyOf rdf:resource="&obo;RO_0002162"/>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002162 -->
<owl:ObjectProperty rdf:about="&obo;RO_0002162">
<rdfs:label rdf:datatype="&xsd;string">in taxon</rdfs:label>
<rdfs:comment rdf:datatype="&xsd;string">Connects a biological entity to its taxon of origin.</rdfs:comment>
<obo:IAO_0000119>PMID:17921072</obo:IAO_0000119>
<obo:IAO_0000115>x is in taxon y if an only if y is an organism, and the relationship between x and y is one of: part of (reflexive), developmentally preceded by, derives from, secreted by, expresses.</obo:IAO_0000115>
<obo:IAO_0000117>Jennifer Deegan</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PMID:20973947</obo:IAO_0000119>
<rdfs:domain rdf:resource="&obo;BFO_0000001"/>
<rdfs:range rdf:resource="&obo;BFO_0000004"/>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="&obo;RO_0002206"/>
<rdf:Description rdf:about="&obo;RO_0002162"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="&obo;RO_0002258"/>
<rdf:Description rdf:about="&obo;RO_0002162"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="&obo;BFO_0000050"/>
<rdf:Description rdf:about="&obo;RO_0002162"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="&obo;RO_0002215"/>
<rdf:Description rdf:about="&obo;RO_0002162"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="&obo;RO_0002214"/>
<rdf:Description rdf:about="&obo;RO_0002162"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="&obo;RO_0002217"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="&obo;BFO_0000051"/>
<rdf:Description rdf:about="&obo;RO_0002162"/>
</owl:propertyChainAxiom>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002163 -->
<owl:ObjectProperty rdf:about="&obo;RO_0002163">
<rdfs:label rdf:datatype="&xsd;string">spatially disjoint from</rdfs:label>
<obo:IAO_0000424>BFO_0000051 exactly 0 (BFO_0000050 some ?Y)</obo:IAO_0000424>
<obo:IAO_0000115>A is spatially_disjoint_from B if and only if they have no parts in common</obo:IAO_0000115>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000116 xml:lang="en">There are two ways to encode this as a shortcut relation. The other possibility to use an annotation assertion between two classes, and expand this to a disjointness axiom. </obo:IAO_0000116>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002180 -->
<owl:ObjectProperty rdf:about="&obo;RO_0002180">
<rdfs:label xml:lang="en">has component</rdfs:label>
<rdfs:comment xml:lang="en">For use in recording has_part with a cardinality constraint.</rdfs:comment>
<rdfs:subPropertyOf rdf:resource="&obo;BFO_0000051"/>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002200 -->
<owl:ObjectProperty rdf:about="&obo;RO_0002200">
<rdfs:label xml:lang="en">has phenotype</rdfs:label>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PMID:20971987</obo:IAO_0000119>
<obo:IAO_0000117 xml:lang="en">Robert Hoehndorf</obo:IAO_0000117>
<rdfs:domain rdf:resource="&obo;BFO_0000002"/>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
<rdfs:subPropertyOf rdf:resource="&owl;topObjectProperty"/>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002201 -->
<owl:ObjectProperty rdf:about="&obo;RO_0002201">
<rdf:type rdf:resource="&owl;FunctionalProperty"/>
<rdfs:label xml:lang="en">phenotype of</rdfs:label>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000119 xml:lang="en">PMID:20971987</obo:IAO_0000119>
<obo:IAO_0000117 xml:lang="en">Robert Hoehndorf</obo:IAO_0000117>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
<owl:inverseOf rdf:resource="&obo;RO_0002200"/>
<rdfs:subPropertyOf rdf:resource="&owl;topObjectProperty"/>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002202 -->
<owl:ObjectProperty rdf:about="&obo;RO_0002202">
<rdf:type rdf:resource="&owl;TransitiveProperty"/>
<rdfs:label xml:lang="en">develops from</rdfs:label>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000117>Melissa Haendel</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Terry Meehan</obo:IAO_0000117>
<rdfs:comment>This is the transitive form of the develops from relation</rdfs:comment>
<obo:IAO_0000115>x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y</obo:IAO_0000115>
<rdfs:domain rdf:resource="&obo;BFO_0000004"/>
<rdfs:range rdf:resource="&obo;BFO_0000004"/>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
<rdfs:subPropertyOf rdf:resource="&obo;RO_0002258"/>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002203 -->
<owl:ObjectProperty rdf:about="&obo;RO_0002203">
<rdf:type rdf:resource="&owl;TransitiveProperty"/>
<rdfs:label xml:lang="en">develops into</rdfs:label>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">David Osumi-Sutherland</obo:IAO_0000117>
<obo:IAO_0000117 xml:lang="en">Terry Meehan</obo:IAO_0000117>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
<owl:inverseOf rdf:resource="&obo;RO_0002202"/>
<rdfs:subPropertyOf rdf:resource="&obo;RO_0002286"/>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002204 -->
<owl:ObjectProperty rdf:about="&obo;RO_0002204">
<rdfs:label xml:lang="en">gene product of</rdfs:label>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000115>definition "x has gene product of y if and only if y is a gene (SO:0000704) that participates in some gene expression process (GO:0010467) where the output of that process is either y or something that is ribosomally translated from x"</obo:IAO_0000115>
<rdfs:range rdf:resource="&obo;BFO_0000002"/>
<rdfs:domain rdf:resource="&obo;BFO_0000004"/>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
<rdfs:subPropertyOf rdf:resource="&owl;topObjectProperty"/>
</owl:ObjectProperty>
<owl:Axiom>
<obo:IAO_0000232>TODO: make this more specific</obo:IAO_0000232>
<owl:annotatedTarget rdf:resource="&obo;BFO_0000002"/>
<owl:annotatedSource rdf:resource="&obo;RO_0002204"/>
<owl:annotatedProperty rdf:resource="&rdfs;range"/>
</owl:Axiom>
<owl:Axiom>
<obo:IAO_0000232>TODO: make this more specific</obo:IAO_0000232>
<owl:annotatedTarget rdf:resource="&obo;BFO_0000004"/>
<owl:annotatedSource rdf:resource="&obo;RO_0002204"/>
<owl:annotatedProperty rdf:resource="&rdfs;domain"/>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/RO_0002205 -->
<owl:ObjectProperty rdf:about="&obo;RO_0002205">
<rdfs:label xml:lang="en">has gene product</rdfs:label>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000112>every HOTAIR lncRNA is the gene product of some HOXC gene</obo:IAO_0000112>
<obo:IAO_0000115>x has gene product y if and only if x is a gene (SO:0000704) that participates in some gene expression process (GO:0010467) where the output of that process is either y or something that is ribosomally translated from y</obo:IAO_0000115>
<obo:IAO_0000112>every sonic hedgehog protein (PR:000014841) is the gene product of some sonic hedgehog gene</obo:IAO_0000112>
<rdfs:domain rdf:resource="&obo;BFO_0000002"/>
<rdfs:range rdf:resource="&obo;BFO_0000004"/>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
<owl:inverseOf rdf:resource="&obo;RO_0002204"/>
<rdfs:subPropertyOf rdf:resource="&owl;topObjectProperty"/>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002206 -->
<owl:ObjectProperty rdf:about="&obo;RO_0002206">
<rdfs:label xml:lang="en">expressed in</rdfs:label>
<obo:IAO_0000115>x expressed in y if and only if there is a gene expression process (GO:0010467) that occurs in y, and one of the following holds: (i) x is a gene, and x is transcribed into a transcript as part of the gene expression process (ii) x is a transcript, and the transcription of x is part of the gene expression process (iii) x is a mature gene product such as a protein, and x was translated or otherwise processes from a transcript that was transcribed as part of this gene expression process</obo:IAO_0000115>
<obo:IAO_0000112>'neural crest cell' SubClassOf expresses some 'Wnt1 gene'</obo:IAO_0000112>
<obo:IAO_0000117 xml:lang="en">Chris Mungall</obo:IAO_0000117>
<rdfs:domain rdf:resource="&obo;BFO_0000002"/>
<rdfs:range rdf:resource="&obo;BFO_0000004"/>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
<rdfs:subPropertyOf rdf:resource="&owl;topObjectProperty"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="&obo;RO_0002206"/>
<rdf:Description rdf:about="&obo;BFO_0000050"/>
</owl:propertyChainAxiom>
</owl:ObjectProperty>
<owl:Axiom>
<obo:IAO_0000232>TODO: make this more specific</obo:IAO_0000232>
<owl:annotatedTarget rdf:resource="&obo;BFO_0000004"/>
<owl:annotatedSource rdf:resource="&obo;RO_0002206"/>
<owl:annotatedProperty rdf:resource="&rdfs;range"/>
</owl:Axiom>
<owl:Axiom>
<rdfs:comment>Example: if g1 is expressed in a hippocampus, and every hippocampus is part of some brain, then g1 is expressed in a brain</rdfs:comment>
<owl:annotatedSource rdf:resource="&obo;RO_0002206"/>
<owl:annotatedProperty rdf:resource="&owl;propertyChainAxiom"/>
<owl:annotatedTarget rdf:parseType="Collection">
<rdf:Description rdf:about="&obo;RO_0002206"/>
<rdf:Description rdf:about="&obo;BFO_0000050"/>
</owl:annotatedTarget>
</owl:Axiom>
<owl:Axiom>
<obo:IAO_0000232>TODO: make this more specific</obo:IAO_0000232>
<owl:annotatedTarget rdf:resource="&obo;BFO_0000002"/>
<owl:annotatedSource rdf:resource="&obo;RO_0002206"/>
<owl:annotatedProperty rdf:resource="&rdfs;domain"/>
</owl:Axiom>
<!-- http://purl.obolibrary.org/obo/RO_0002207 -->
<owl:ObjectProperty rdf:about="&obo;RO_0002207">
<rdfs:label xml:lang="en">directly develops from</rdfs:label>
<obo:IAO_0000117>David Osumi-Sutherland</obo:IAO_0000117>
<rdfs:comment>TODO - add child relations from DOS</rdfs:comment>
<obo:IAO_0000115>Candidate definition: x directly_develops from y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p, and a substantial portion of the matter of y comes from x, and the start of x is coincident with or after the end of y</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000117>has developmental precursor</obo:IAO_0000117>
<obo:IAO_0000119>FBbt</obo:IAO_0000119>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
<rdfs:subPropertyOf rdf:resource="&obo;RO_0002202"/>
<rdfs:domain>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="&obo;CARO_0010000"/>
<rdf:Description rdf:about="&obo;CL_0000000"/>
</owl:unionOf>
</owl:Class>
</rdfs:domain>
<rdfs:range>
<owl:Class>
<owl:unionOf rdf:parseType="Collection">
<rdf:Description rdf:about="&obo;CARO_0010000"/>
<rdf:Description rdf:about="&obo;CL_0000000"/>
</owl:unionOf>
</owl:Class>
</rdfs:range>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002210 -->
<owl:ObjectProperty rdf:about="&obo;RO_0002210">
<rdfs:label xml:lang="en">directly develops into</rdfs:label>
<obo:IAO_0000118>developmental precursor of</obo:IAO_0000118>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
<rdfs:subPropertyOf rdf:resource="&obo;RO_0002203"/>
<owl:inverseOf rdf:resource="&obo;RO_0002207"/>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002211 -->
<owl:ObjectProperty rdf:about="&obo;RO_0002211">
<rdfs:label xml:lang="en">regulates</rdfs:label>
<obo:IAO_0000117>Tanya Berardini</obo:IAO_0000117>
<obo:IAO_0000115>x regulates y if and only if x is a process and y is either a process or a quality, and the progression of x exerts an effect on the frequency, rate or exteny of y</obo:IAO_0000115>
<obo:IAO_0000117>Chris Mungall</obo:IAO_0000117>
<obo:IAO_0000117>David Hill</obo:IAO_0000117>
<obo:IAO_0000119>GO</obo:IAO_0000119>
<rdfs:domain rdf:resource="&obo;BFO_0000007"/>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="&obo;RO_0002230"/>
<rdf:Description rdf:about="&obo;RO_0002211"/>
</owl:propertyChainAxiom>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="&obo;RO_0002211"/>
<rdf:Description rdf:about="&obo;BFO_0000050"/>
</owl:propertyChainAxiom>
</owl:ObjectProperty>
<!-- http://purl.obolibrary.org/obo/RO_0002212 -->
<owl:ObjectProperty rdf:about="&obo;RO_0002212">
<rdfs:label xml:lang="en">negatively regulates</rdfs:label>
<obo:IAO_0000115>x negatively regulates y if and only if x is a process and y is either a process or a quality, and the progression of x reduces the frequency, rate or exteny of y</obo:IAO_0000115>
<obo:IAO_0000114 rdf:resource="&obo;IAO_0000125"/>
<rdfs:subPropertyOf rdf:resource="&obo;RO_0002211"/>
<owl:propertyChainAxiom rdf:parseType="Collection">
<rdf:Description rdf:about="&obo;RO_0002230"/>
<rdf:Description rdf:about="&obo;RO_0002212"/>
</owl:propertyChainAxiom>
</owl:ObjectProperty>